What is the appropriate time, temperature, and pressure for sterilizing packaged instruments in an autoclave?

The appropriate time, temperature, and pressure for sterilizing packaged instruments in an autoclave is 15-20 minutes at 250°F with 15 psi. This method is widely recognized for effectively achieving sterilization by using steam under pressure. The specified temperature and pressure ensure that microorganisms, including bacteria and viruses, are destroyed, and the duration allows for adequate penetration of steam into the packaged instruments.

At 250°F with 15 psi, the steam has sufficient energy to effectively kill pathogens without damaging the instruments, provided that the exposure time meets the recommended duration. This balance of time, temperature, and pressure is key to ensuring the sterilization process is thorough and effective, particularly for packaged items that may require steam to reach all surfaces, ensuring that the instruments are safe for use.

Other options do not align with the standard guidelines for steam sterilization; they either involve incorrect temperatures or durations that may not guarantee effective sterilization.